學經歷

1. 國立台灣大學園藝學系 學士
2. 國立台灣大學園藝學研究所 碩士
3. 國立台灣大學園藝學研究所 博士
4. 美國加州大學戴維斯分校藥理與毒理學系 博士後研究員
5. 國立中興大學食品科學系 博士後研究員

教授科目

園產品加工學、園藝植物化學、園產品分析與實習一 、園產品分析與實習二、高級園產品加工學、免疫分析技術 ( 生技學程 )

專長

近年研究重點

1. 探討蕈菇類免疫調節蛋白的純化、選殖、製備、調節免疫活性、作用機轉、體內作用。
2. 其他中草藥、保健植物萃取物之免疫調節作用及其他生理活性評估。
3. 園產品及機能性食品、營養生化、社區營養、社區保健的相關研究。

主要校內服務:

1. 國立台灣大學生物技術研究中心 產學合作組組長 (2005-)
2. 國立台灣大學農學院食品與生物分子研究中心 儀器組組長 (2005-)

學術專業團體歷任服務:

1. 台灣保健食品學會 副秘書長
2. 台灣食品科技發展學會 學術委員會 食品加工組 召集人
3. 台灣醫用營養醫學會 理事
4. 台灣農業資訊科技發展學會 理事

著作與論文 (since 2005)

1. Sheu F*, Chien PJ, Hsieh KY, Chin KL, Huang WT, Tsao CY, Chen, YF, Cheng HC, Chang HH. 2009. Purification, Cloning and Functional Characterization of a Novel Immunomodulatory Protein from Antrodia camphorata (Bitter Mushroom) that Exhibits TLR2-Dependent NF-κB Activation and M1-Polarization within Murine Macrophages. J. Agric. Food Chem. (SCI, in press)
2. Yeh CH, Hsiao JK, Wang JL, Sheu F*. 2009. Immunological Impact of Magnetic Nanoparticles (Ferucarbotran) on Murine Peritoneal Macrophages. Journal of Nanoparticle Research. (SCI, in press)
3. Sheu F*. 2008. Traceability in Taiwan: Progress, Status and Implementation of Information Technology. Afro-Asian Journal of Rural Development. 41(1): 7-15.
4. Tong MH, Chien PJ, Chang HH, Tsai MJ, Sheu F*. 2008. High Processing Tolerances of Immunomodulatory Proteins in Enoki and Reishi Mushrooms. J. Agric. Food Chem. 56(9): 3160-3166. (SCI)
5. Peng S, Cheng CY, Sheu F, Su CH. 2008. The antimicrobial activity of heyneanol A extracted from root of taiwanese wild grape. J. Appl. Microbiol. 105(2): 485-91. (SCI)
6. Huang YL, Sheu F, Lee MH, Chau CF. 2008. Effects of particle size reduction of insoluble fibres by micron technology on different caecal and faecal indices. Journal of the Science of Food and Agriculture. 88: 435-441. (SCI)
7. Huang YL, Yen GC, Sheu F, Chau CF. 2008. Effects of Water-Soluble Carbohydrate Concentrate from Chinese Jujube on Different Intestinal and Fecal Indices. J. Agric. Food Chem.; 56(5); 1734-1739. (SCI)
8. Chen YY, Chang HH, Lee HY, Sheu F*. 2008. Immunomodulatory and Anti-tumor Effects of Oral Administration with Antrodia cinnamomea Fruting Bodies in BALB/c Mice. Taiwan Journal of Agricultural Chemistry and Food Science. 46(2): 1-9.
9. Chang HH, Chien PJ, Tong MH, Sheu F*. 2007. Mushroom Immunomodulatory Proteins Possess Potential Thermal/Freezing Resistance, Acid/Alkali Tolerance and Dehydration Stability. Food Chem. 105: 597-605. (SCI)
10. Fuu Sheu*, Po-Jung Chien, His-Kai Wang, Hui-Hsin Chang, Yuan-Tay Shyu. 2007. New Protein PCiP from Edible Golden Oyster Mushroom Pleurotus citrinopileatus Activating Murine Macrophages and Splenocytes. Journal of the Science of Food and Agriculture. 87(8): 1550-1558. (SCI)
11. Sheu, F., Chuang, W. I., Chien, P. J. 2007. Citri Reticulatae Pericarpium extract Suppress Adipogenesis in 3T3-L1 Preadipocytes. J. Sci. Food Agric. 87(13): 2382-2389. (SCI)
12. Chang HH, Sheu F*. 2007. A novel fungal immunomodulatory protein (PCP) isolated from Poria cocos activates mouse peritoneal macrophage involved in toll-like receptor 4. FASEB JOURNAL 21 (6): A738-A738. (SCI)
13. Po-Jung Chien, Fuu Sheu and Feng-Hsu Yang. 2007. Effects of edible chitosan coating on quality and shelf life of sliced mango fruit. Journal of Food Engineering. 78(1): 225-229. (SCI)
14. Chien, P. J., Sheu, F., Lin, H. R. 2007. Coating Citrus (Murcott tangor) Fruit with Low Molecular Weight Chitosan Increases Postharvest Quality and Shelf Life, Food Chemistry. 100(3): 1160-1164. (SCI)
15. Chien, P. J., Sheu, F., Huang, W. T. , Su, M. S. 2007. Effect of molecular weight of chitosans on their antioxidative activities in apple juice. Food Chem. 102(4): 1192-1198. (SCI)
16. Chien, P. J., Sheu, F., Lin, H. R. 2007. Quality Assessment of Low Molecular Weight Chitosan Coating on Sliced Red Pitayas. Journal of Food Engineering. 79: 736-740. (SCI)
17. Huang YL, Yen GC, Sheu F, Lin JY, Chau CF. 2007. Dose effects of the food spice cardamom on aspects of hamster gut physiology. MOLECULAR NUTRITION & FOOD RESEARCH 51 (5): 602-608. (SCI)
18. Chang HH, Sheu F. 2006. Anti-tumor mechanisms of orally administered a fungal immunomodulatory protein from Flammulina velutipes in mice. FASEB JOURNAL 20 (5): A1057-A1057 Part 2. (SCI)
19. Po-Jung Chien, Ying-Chen Chen, Shou-Chin Lu, Fuu Sheu. 2005. Dietary Flavonoids Suppress Adipogenesis in 3T3-L1 Preadipocytes. J. Food Drug Analy. 53: 168-175. (SCI)
20. Chi-Fai Chau, Fuu Sheu, Ya-Ling Huang and Ching-Yi Lin. 2005. Improvement in Intestinal Function and Health by the Pomace Fibre Derived from Citrus sinensis L. cv. Liucheng. Journal of the science of food and agriculture. 85(7): 1211-1216. (SCI)
21. Tsai CC, Chang JS, Sheu F, Shyu YT, Yu AYC, Wong SL, Dai CF, Lee TM. 2005. Seasonal growth dynamics of laurencia papillosa and gracilaria coronopifolia from a highly rutrophic reef in southern Taiwan: temperature limitation and nutrient availability. Journal of Experimental Marine Biology and Ecology. 315(1): 49-49. (SCI)
22. Chien, P. J., Sheu, F. ,Shyu, Y. T. and Yen, G. C. (2005) Enzymatic Hydrolyzing for Naringin Increase Antioxidant Activity of Grapefruit Juice. Food Sci. Agri. Chem. 43(1): 30 – 37.
23. Lee TM, Tsai PF, Shyu YT, Sheu F. 2005. The effects of phosphite on phosphate starvation responses of Ulva lactuca (Ulvales, Chlorophyta). JOURNAL OF PHYCOLOGY 41 (5): 975-982.

專利:

1. Protein ACA1 of Antrodia Camphorata. US patten apply code: 11/015,078 (12/18/04)
2. 口服飛益福 (FIP-fve) 於抗腫瘤的應用. 2007. (我國專利證書號 I277423)
3. 樟芝之新蛋白阿卡安１(ACA1). 2007. (我國專利證書號 I285207)

專利申請中:

1. 我國專利申請
   分離金針姑免疫調節蛋白飛益幅 (FIP-fve)之方法. (我國專利審查中, 案號: 096108865)
2. 我國專利申請
   白木耳之新免疫調節蛋白台福平(TFP). (我國專利審查中, 案號: 096120268)

技術轉移:

• 複方保健植物飲料之開發. 2006. 技術轉移至味全食品工業股份有限公司.
• EcgoGuard 天然保健配方. 2008. 技術轉移至東阪國際有限公司.
• 保健金針菇檸檬果汁配方技術及飛益福於抗腫瘤應用專利. 2008. 技術轉移至味全食品工業股份有限公司.